Clostridium novyi causing necrotising fasciitis in an injecting drug user

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Clostridium novyi causing necrotising fasciitis in an injecting drug user.

Necrotising fasciitis with pronounced local oedema is described in an injecting drug user. Clostridium novyi was an unexpected single pathogen isolated from infected tissue. The patient was among a cluster of cases, all injecting drug users, presenting with toxaemia and soft tissue infection. The causal role and pathogenicity of C novyi is discussed.

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Clostridium novyi infection: a fatal association with injecting drug users.

Injecting drug users frequently use accident and emergency (A&E) departments to access emergency care for local and systemic infections. Clostridium novyi type A is a bacterium that has recently been associated with a number of fatalities among drug injecting addicts. The clinical course is described of a patient who attended an A&E department with septicaemia who was found at postmortem examin...

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CASE REPORTS Clostridium novyi infection: a fatal association with injecting drug users

Injecting drug users frequently use accident and emergency (A&E) departments to access emergency care for local and systemic infections. Clostridium novyi type A is a bacterium that has recently been associated with a number of fatalities among drug injecting addicts. The clinical course is described of a patient who attended an A&E department with septicaemia who was found at postmortem examin...

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Clostridium perfringens type C causing necrotising enteritis.

A rapidly fatal case of enteritis necroticans in a 24 year old man with diabetes was caused by Clostridium perfringens type C. The role of beta toxin in the disease is discussed. This type has not been previously described as a causative agent in necrotising bowel disease of man outside endemic areas.

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Necrotising Fasciitis

Be aware that: Necrotising fasciitis is difficult to diagnose in its initial stages, as it mimics cellulitis. Important early clues are pain, tenderness and systemic illness out of proportion to the localised physical signs. Bullae and ecchymotic skin lesions also point to the condition (and are not normally found with cellulitis). [2] A high index of suspicion is necessary and suspected cases ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2002

ISSN: 0021-9746

DOI: 10.1136/jcp.55.2.141